![]() Note: Please follow the steps in our documentation to enable e-mail notifications if you want to receive the related email notification for this thread. To open Outlook in safe mode, right-click the Start button > click Run > type Outlook.exe /safe, and click OK. ![]() Select the profile you want and click on OK. You will now be asked which profile to use. To confirm which add-ins is the cause of this issue, you can re-enable add-ins one by one until this issue occurs again. The file c:UsersAppDataLocalMicrosoftOutlook<> is not an Outlook data file (ost). Press the Windows Key + R and type in Outlook /safe followed by enter.If you have extra questions about this answer, please click "Comment". If Outlook works well in safe mode, then this issue is caused by add-ins. The attempt to log on to Microsoft Exchange has failed. I get the error: 'Cannot start Microsoft Outlook. My Office 2016 Outlook was working fine, but then I started to get the following message every time I try to open Outlook: Cannot start Microsoft Outlook. Windows 10 21H2 (OS Build 19044.1706) Office 365 2204 (Build 15128.20178) Im unable to launch Outlook 365 offline. If the answer is helpful, please click "Accept Answer" and kindly upvote it. AO Alan Outlook Created on OctoCannot start Microsoft Outlook. For more information, please refer to: End of support for Office 2010. For your better user experience, it is recommended that you use a newer version of office. ![]() Since the support for Office 2010 ended on October 13, 2020, and there will be no extensions and extended security updates, you can still use your office programs. Threats include any threat of suicide, violence, or harm to another. On the other hand, considering that you have encounter the password prompt issue, it's suggested that you could refer to the following thread to troubleshooting: Why does Outlook keep prompting for password. Harassment is any behavior intended to disturb or upset a person or group of people. (It might take a few moments for the Apps list to load). Scan your system for viruses, Trojans, spyware, and other malware. According to your description, it's suggested that you could create a new Outlook profile (Control Panel>Mail>Show Profiles>add) and then add your accounts to check if there're any differences. Quick Repair From Start select Settings to launch Windows Settings From Windows Settings choose Apps. Clear the check boxes next to the add-ins you want to disable.
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